Posted by hopefullynow on May 27, 2010, at 13:58:34
In reply to Advice please re. clomipramine/anafranil, posted by kizzie2 on May 27, 2010, at 4:42:14
Hello,
Anafranil is a very potent AD, even in small doses.I am currently on Anafranil 100mg/day and in the very beginning i started with 10 mg pills.I felt an robust improvement even at this small dose.What I felt when i increased to 100 mg/day, was that the major improvement were at relative small doses 50-75 mg, when i reached 150 mg/day the side effects couteracted the feelin good sensation and the diffenece in efficacity was minimal.
Anafranil is a very potent AD which targets serotonin in the first place and norepinephrine in the second.Thru his 5-HT2a antagonism it should target dopamine, but i don't think it does too much as long as I encounter elevated prolactine levels.
For me Anafranil is the foundation of the treatment but I had to introduce in my regimen an norephrinergic agent to reach remission.First was maprotiline, but being too sedating, now i'm experiencing with low dose Wellbutrin with nice results.
Best regards!
poster:hopefullynow
thread:949082
URL: http://www.dr-bob.org/babble/20100524/msgs/949117.html