Posted by Brainbeard on August 31, 2010, at 6:17:22
In reply to Re: Desipramine or Dexedrine? » Maxime, posted by Conundrum on August 30, 2010, at 12:59:24
Desipramine is very different from nortriptyline. Desipramine is an ultra-potent NRI (noradrenaline reuptake inhibitor). Nortriptyline is only moderately strong as an NRI. Nortriptyline is also sedating, which desipramine is not. Desipramine is therefore more activating and is in fact sometimes used for treating ADD and the like. Side-effects like tachycardia (fast heartbeat) are more likely with desipramine. Nortriptyline, finally, also works on serotonin in high doses (SRI), which desipramine does not. Oh, and nortriptyline promotes deep sleep, which desipramine does not.
Current meds: clomipramine 187.5mg, fluvoxamine (Luvox) 50mg, bethanechol 25-50mg.
PRN: modafinil, oxazepam, dextro-amphetamine, Concerta/Ritalin (methylphenidate), gabapentin (Neurontin).
poster:Brainbeard
thread:960521
URL: http://www.dr-bob.org/babble/20100829/msgs/960767.html