Re: Differing AD effects on DHEA

Posted by linkadge on July 28, 2010, at 13:49:01

In reply to Re: Differing AD effects on DHEA, posted by morgan miller on July 28, 2010, at 10:45:43

There has been more than one study on lithium on DHEA / DHEA-S levels. There was a in vivo, human study which concluded theraputic doses lower DHEA/S.
DHEA interacts with the sigma-1r receptor. Sigma agonists like DHEA have antidepressant and neuroprotective effects. Low DHEA could possibly produce apathy, low energy and/or sexual dysfunction.
OTOH, mania might be associated with elevated DHEA and hence this might be part of the antimanic effect of lithium.

Linkadge

Thread

Differing AD effects on DHEA linkadge 7/27/10
Re: + bupropion increases DHEA (nm) linkadge 7/27/10
Re: Differing AD effects on DHEA morgan miller 7/28/10
Re: Differing AD effects on DHEA linkadge 7/28/10
Re: Differing AD effects on DHEA europerep 7/28/10
Re: Differing AD effects on DHEA morgan miller 7/28/10
Re: Differing AD effects on DHEA morgan miller 7/28/10
Re: Differing AD effects on DHEA morgan miller 7/28/10
Re: Differing AD effects on DHEA europerep 7/29/10
Re: Differing AD effects on DHEA morgan miller 7/29/10

Post a new follow-up

Notify the administrators

Start a new thread

poster:linkadge thread:956152
URL: http://www.dr-bob.org/babble/20100720/msgs/956219.html

	for
in