Re: anti-cholinergic AD's = therapeautic efficacy

Posted by linkadge on July 15, 2010, at 14:11:38

In reply to Re: anti-cholinergic AD's = therapeautic efficacy » SLS, posted by rovers95 on July 14, 2010, at 17:40:14

Monoamine reuptake inhibitors have some downstream anticholinergic effects in their own right. NRI's especially produce anticholinergic like effects even when the molecule has no cholinergic affinity. M1 antagonists especially, appear to have antidepressant effects. Mice lacking m1 receptors are particularly responsive to amphetamines due to increased cortical DA release.
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anti-cholinergic AD's = therapeautic efficacy rovers95 7/14/10
Re: anti-cholinergic AD's = therapeautic efficacy SLS 7/14/10
Re: anti-cholinergic AD's = therapeautic efficacy » SLS rovers95 7/14/10
Re: anti-cholinergic AD's = therapeautic efficacy linkadge 7/15/10

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