Posted by Conundrum on July 5, 2010, at 20:24:59
In reply to Ritalin, Amineptine And Dextro-Amphetamine., posted by Brainbeard on July 5, 2010, at 13:14:36
> Ritalin/methylphenidate has strong noradrenergic effects too.
>
> I have used amineptine and it is a very, very subtle drug, at least in normal therapeutic doses. It doesn't have a long half-life; the half-life of the drug itself is less than an hour, and the half-life of the metabolites is about 2.5 hours. The effects on the brain probably last much longer.
>
> Personally, I find dextro-amphetamine a much cleaner drug than Ritalin/methylphenidate.
>
>
Could you explain what you mean by dextroamphetamine being cleaner than ritalin? It doesn't increase heart rate and cause palpitations as must as ritalin? Perhaps the increase in serotonin smooths it out a bit? The only thing ritalin ever did for me was make my heart beat faster and talk kind of fast at high doses. I wouldn't say it was a pleasant effect. Normal doses did less than the occasion cup of sumatra.I wonder if amphetamine working as a substrate on norepinephrine transporters causes the release of dopamine as well as norepinephrine?
Also could you describe more your experience with amineptine? What were its effects? If it were available would you keep taking it? Its interesting that you said it was subtle and yet it has been removed from world markets.
Post-SSRI syndrome: iatrogenic anhedonia, memory and concentration problems, sexual dysfunction. [NOTE no sadness or anxiety]
Location:USA
Currently taking 300mg Lamictal and 30mg mirtazapine.
poster:Conundrum
thread:953012
URL: http://www.dr-bob.org/babble/20100628/msgs/953426.html