Posted by Conundrum on July 5, 2010, at 8:29:30
In reply to Re: mirapex, posted by Brainbeard on July 5, 2010, at 4:34:39
I know your not the first one to mention amphetamine, I think Rjlockhart did as well. (hope i remembered is username right). However it causes more release of norepinephrine and serotonin, so its hard to get a subjective idea of what you are actually feeling when you take an amphetamine. I think ritalin would be a closer bet, since it binds more to dopamine than norepinephrine reuptake sites, which is the opposite of amphetamines and doesn't inhibit the uptake of serotonin.
I know that ritalin binds more to the dopamine transporter than dextroamphetamine, but I'm sure amphetamines RELEASE more of both catecholamines.
I mean if you really wanna get the definitive dopaminergic drug you're gonna have to try amineptine. Its closest to pure dopamine reuptake inhibitor of which I am aware. It uses your own brains dopamine, so its not going to make you very compulsive like a agonist which acts more potently than the natural stuff. It has a long half life so its not as addictive as amphetamines and I belive it is dosed once a day. Also it doesn't block the D2 receptor like antipyschotics, so it shouldn't cause tardive symptoms. You could probably develop tics like with ritalin however.
Post-SSRI syndrome: iatrogenic anhedonia, memory and concentration problems, sexual dysfunction. [NOTE no sadness or anxiety]
Location:USA
Currently taking 300mg Lamictal and 30mg mirtazapine.
poster:Conundrum
thread:953012
URL: http://www.dr-bob.org/babble/20100628/msgs/953355.html