Posted by zonked on June 18, 2010, at 20:08:54
In reply to trying to choose an MAOI???, posted by Roslynn on June 18, 2010, at 16:24:38
This sounds cliche--but since I have taken all four, I think I can comment. :-)
Parnate was more "activating" to me, and did NOT cause me to gain weight. It was not activating in an anxiety-causing way for me, although it has had this effect on some people. It also helped somewhat with my ADD (it has properties similar to Dexedrine/Adderall/Amphetamine.)
Nardil was definately less "activating"; but relieved depression just as well. It is considered the "gold standard" if you have social/generalized anxiety, and I can see why. I could talk to anyone about anything on either of these when they were working; but with Nardil it was more of a calm/at ease/fuzzy feeling whereas with Parnate it was a bit stimulant-like. If that makes sense.
Nardil made me gain a lot of weight--40lbs in about a year and a half; Parnate did not. Nardil made me crave sugary/salty/savory foods, Parnate did not.
Both are the best drugs I've ever taken for depression--if you don't mind me asking, what is your DX/what are your symptoms? Other folks here, I'm sure, will weigh in also.
Selegiline made me way too anxious (don't remember the dose, but it was in pill form).
I am on 60mg Marplan now and it's too early to give a final verdict, but it *seems* somewhere in between Nardil and Parnate in terms of activation and has reduced my appetite. It's working for my depression, but it's too early to objectively tell how well or how evenly.
Best of luck to you, I'm sure you'll find the right MAOI for you, and glad you have a doc who'll prescribe them.
-z
> Hi everyone,
>
> My pdoc has finally come to the point where he feels we have exhausted other options for meds and he wants me to try an MAOI. (I was on EMSAM which worked a little but I had terrible rashes).
>
> It seems to be between Nardil, Parnate and Selegiline. What are the major differences between them? And why did my pdoc not mention Marplan as a choice, when it seems a few people here are taking it?
>
> Thank you for any help!
>
> Roslynn
poster:zonked
thread:951439
URL: http://www.dr-bob.org/babble/20100615/msgs/951445.html