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Vitamin D3 and fatigue

Posted by Klaus on May 21, 2010, at 16:49:14

Hello,

for 3 years I am struggling with depression and fatigue and recently I had my 25(OH)D3 checked which turned out to be very low (6.3ng/ml).
Due to my low level I started supplementing Vitamin D3 and noticed a strong increase in fatigue and depression. I have been successfully taking Selegiline/Deprenyl (MAO-B inhibitor) for some months against my fatigue and depression but once I start taking Vitamin D3 it doesn't seem to have any effect anymore. Once the Vitamin D3 dose has worn off again (which might take weeks) I magically feel better. I tried low doses of Vitamin D3 (200IU), high doses (5000IU), dry tablets and gelcaps and always come up with the same result. I also tried magnesium (as glycinate 600mg) and calcium (800mg) - no success. I understand that Vitamin D3 plays a big role and it is definitely recommended to increase my levels. However, what is the reason of this fatigue???? I spent hours googling a possible reason.. but didn't come up with a definite answer. I found things like die-off symptoms (herxheimer), magnesium deficiency, autoimmune diseases (sarcoidosis...),... It is much easier to cope with this Vitamin D3 induced fatigue if I know the reason of these adverse effects. A friend of mine (a healthy person) complains about similar issues after taking 4000IU for several days.

- Does anybody have similar experience with Vitamin D3? If yes, did the fatigue resolve after some time?

- Does anybody know a possible reason of these effects?


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poster:Klaus thread:948201
URL: http://www.dr-bob.org/babble/20100514/msgs/948201.html