Posted by SLS on May 10, 2010, at 15:26:45
In reply to Re: Interesting article? What do you think? » SLS, posted by 49er on May 10, 2010, at 9:32:32
I doubt that I could find an investigation that was designed to establish such statistics other than the STAR*D study.
> The Star D study was reporting 67% but that is the best I have seen.
That is pretty good when you consider that each subject was given only four treatments out of the many that are available. The 67% they reported was for remission. The rate of response (defined as a 50% reduction in depression scores) must have been substantially higher. I don't think 75% is out of the question. I guess we can't know for sure.
> Do you have a link to that study?
> I know that is an unfair question as I will see studies and then forget where I saw them at.
I appreciate your letting me off the hook here.
:-)
> > It is significant that when working with inpatients or people with more severe depressions, the placebo response rate plunges.
> I will have to look up the statistics for inpatient folks and placebo rates. I haven't seen any studies on that. If you have link, that would be appreciated.
It is interesting that the people who would have you believe that antidepressants are no better than placebo must concede that they seem to be effective when severely ill populations are looked at. Khan et al (2002) found that the proportion of studies favoring antidepressants over placebo increased with the severity of depression. The response to placebo declined with increasing severity whereas the response to antidepressants increased.
http://www.ncbi.nlm.nih.gov/pubmed/11799341
- ScottThe measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:946874
URL: http://www.dr-bob.org/babble/20100504/msgs/947007.html