Posted by Atalanta on April 26, 2010, at 8:07:55
In reply to Re: old versus new Nardil formulation » stargazer2, posted by bulldog2 on April 24, 2010, at 14:05:24
> > Yes, I took Nardil at 15 mg BID back in the late 80's with good success, until a doc treating me stopped the Nardil (standard of care then)and I got all of my symptoms back without being able to successfully treat it again.
> >
> > The new formulation just works differntly all together. Many here say that a higher dose is required but I took 30 mg with fair relief as higher doses caused too many SE's. I had a variety of SE's with the newer version beginning with weight gain, hypotension, severe GI symptoms including gas pain and constipation, along with pedal edema. Most of the SE's resolved over time.
> >
> > I have not felt that great on the newer version of Nardil and Marplan (also reformulated). I think there were more changes than the enteric coating with Nardil, although this has been denied. I think it is made somewhere out of the US, so who knows anything about the quality standards of foreign production of meds, including generics. Many generic do not work the same as the brand name (i.e Synthroid).
> >
> > You can Google 'Nardil reformulation', there is a website of many whom petitioned Pfizer to make the original formula without success.
>
> Do you have any theories for the excessive sides? Would the med coming apart in the stomach instead of the intestines possibly be the cause of some of the sides?I suppose breaking down higher up in the digestive tract could cause these additional side effects. It's the seeming lack of efficacy that flummoxes me. I do not know what to do for this patient!
poster:Atalanta
thread:944352
URL: http://www.dr-bob.org/babble/20100425/msgs/945124.html