Posted by bulldog2 on March 7, 2010, at 16:27:23
In reply to Re: Nuerontin for pain and mood » bulldog2, posted by floatingbridge on March 7, 2010, at 10:19:21
> Thanks BD,
>
> Guess that answers the pain question. I have another one--do you (or anyone else) feel it raises the overall tolerance to pain? I was told (true or not) that not only do I have real pain issues, I am also more sensitive (lucky, lucky).
>
> Hmmmm.
>
> fbIt seems as if many depressed people are more sensitive to pain. Including myself! I posted a thread not that long ago about that issue. There seems to be evidence that a subset of depressed people have a shortage of endorphins and have pain issues. To many endorphin receptors sitting out there without an endorphin to partner with.
So that is why some of these endorphin starved depressives respond well to an opiate.
Also many find that once their mood is no longer depressed that their pain lessens. This is from a non opiate antidepressant. Wonder if coming out of depression lifts one's endogenous endorphin levels? Need to look for some studies.
As for neurontin it is often used for neuropathic pain. It seems to have some action with the nmda receptor. But it is more effective for neuropathic pain than other pain issues. I have found that when my mood was good when on neurontin I could tolerate my normal arthritis pain better.
That thread on magnesium and fibromalgia gets into more detail about nmda and pain. There are some links within that might help.
Hope this helped.
poster:bulldog2
thread:938552
URL: http://www.dr-bob.org/babble/20100305/msgs/938859.html