Posted by linkadge on February 26, 2010, at 18:38:59
In reply to Re: Headaches from serotonergic drugs anyone? » linkadge, posted by conundrum on February 24, 2010, at 18:17:20
Too much serotonin can cause headaches. Amitriptyline (and the herb feverfew) appear to work by blocking the action of serotonin at certain receptors.
Cyprohepdadine (a 5-ht2 antagonist) has antimigrane effects.
I think that 5-htd agonists and 5-ht2a antagonists have antimigrane effects. When SSRI's do relieve migranes it may be because of 5-ht1d agonistm.
You may be able to relieve SSRI migrane by taking feverfew or amitriptyline. I remember feverfew combined well with citalopram.
Linkadge
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URL: http://www.dr-bob.org/babble/20100216/msgs/938006.html