Posted by bleauberry on October 16, 2009, at 17:50:13
In reply to Re: Olmifon/Adrafinil dosing, ill effects? » bleauberry, posted by Sunbath on October 16, 2009, at 3:45:57
> Hey thanks a lot Bleauberry for so much detailed informations!
You're welcome! Hey, we're all here to share information and support as best we can.
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> I'm a little bit confused though.. you said that Adrafinil gets better over the first weeks you take it, but I shouldn't expect a stimulant effect except maybe for the first few days?Yes that is correct. My experience as well as the general reports on the internet.
> Will it get stimulating long term then?
Yes and no. It is like a stimulant on demand. It doesn't feel like it is there unless you have a need for stimulation, and then the stimulation is present because the alpha-1 receptors are easily stimulated when needed, but not when not needed. Kind of like Viagra...it won't do anything without arousal. Will Viagra automatically make a man hard? Well, without stimulation, usually no. With stimulation, usually yes quite so.
> If I got it right it sounds ideal to me.. I don't want a stimulant that "kicks in fast", feels like a drug and develops tolerance in me.. it sounds far better to have something that almost works like someone would expect it from an antidepressant :)
That's pretty much my experience with it as well as what is reported from most people who have used it for a least a couple or more months. It becomes invisible. But as you look around at yourself and compare to how you used to be months ago, it becomes obvious you have more energy and performance than you used to but you aren't aware it is drug-induced. Theory is that it is the alpha-1 receptors re-adapted to be more sensitive.
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> Regarding the milk thistle: that sounds great if it prevents liver damage to some extent, thanks a lot for this tip. But would you also tell me a good preparation I should buy, or is it not so important to chose the "right" extract like with st.john's wort and other standardized, patented extracts? Are there some characteristics (potency, or solvent used) the extract I buy should meet?I think most brands on the market are of good quality. Look for ones with specified amounts of the active ingredient. Look for capsules.
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> Thank you!!
But again, the MAOI component makes all of this deserve respect and caution, especially in the early days/weeks. There is not enough research on the MAOIs to predict interactions or reactions with many substances, other than the obvious known ones. I personally do not see much risk here, but if it were me I would certainly approach with respect. For example the 75mg starting dose of Adrafinil.
poster:bleauberry
thread:920993
URL: http://www.dr-bob.org/babble/20091012/msgs/921169.html