Posted by bleauberry on October 15, 2009, at 17:01:26
In reply to Olmifon/Adrafinil dosing, ill effects?, posted by Sunbath on October 15, 2009, at 6:36:17
I was on Adrafinil for several years, along with Prozac and Zyprexa. I liked it a lot better than Provigil, but other people like Provigil better. It is an individual trial thing to discover.
I don't think there is an accurate way to do a dose comparison. It migth be ballpark, but the drugs are different, despite being almost identical molecularly.
I started at 150mg, worked up to 600mg, and then dropped down to 300mg where I stayed for years.
Adrafinil works similar to ADs. That is, it can have an immediate energy boost, mood boost, and maybe some aggravation irritation overstimulation thing, and some tiredness afterward sort of like a crash. This goes away in less than a week, or upon reducing the dose, and then to me it became invisible. I couldn't feel anything from it. But everything I had read said it needed at least a month, two months better, three months even better. So I kept taking it.
Sure enough, about 6 weeks later I realized I had good energy, clear-headed, good performance and creativity, motivation, pleasure, and socialness. It overcame the blah apathy of SSRIs pretty well, but it took a while. I never really felt it kick in all of sudden, it just kind of snuck up on me gradually.
I don't think there is any research on combining it with MAOI, and I doubt hardly any anecdotal experience either. So I would go easy. Maybe 75mg for a few days, 150mg, 225mg, work up with a sense of respect for the unknown. It could turn out to be great, and it might not. But you want it to be controlled and careful regardless.
For the liver thing, take Milk Thistle extract everyday and/or get a liver function test 3 times per year. I got my liver tested twice or three times per year but it was always fine. My dose was low at 300mg, so that probably helped.
If you are looking for something that will kick in fast like a stimulant, I think it would be unrealistic to expect that of Adrafinil. You might feel some of that the first couple days, but it works over a period of weeks and months, not days or hours.
poster:bleauberry
thread:920993
URL: http://www.dr-bob.org/babble/20091012/msgs/921035.html