Posted by SLS on October 3, 2009, at 7:48:54
In reply to ED on Wellbutrin and Agomelatine - what gives?!, posted by uncouth on October 2, 2009, at 20:59:21
Serotonin 5-HT2c antagonists prevent erections from occurring. However, they can also increase libido acutely, and produce increased testosterone levels subacutely. There is a balance that must be maintained between 5-ht1a 5-ht2a and 5-ht2c receptor activation to maintain healthy sexual function. I guess this leaves agomelatine as a suspect in producing erectile dysfunction, however, I don't know what to attribute reduced libido to, except that the Geodon might still be having a negative impact on it.
- Scott
poster:SLS
thread:919459
URL: http://www.dr-bob.org/babble/20091001/msgs/919513.html