Posted by Brainbeard on July 30, 2009, at 14:12:45
In reply to Re: any success with dopaminergic meds?, posted by deprime82 on July 30, 2009, at 11:29:13
> piribedil sounds like an option, but i don't know if it's prescribed in europe.
I just bought some from a Greece pharmacy, so yes, it is prescribed in Europe.
Wellbutrin probably doesn't work through dopamine activation at all. See elsewhere on the forum.
Also, dopamine agonist don't activate dopamine, but mimick dopamine at the D2 and sometimes also the D3-receptor. That's a huge difference. If you want pure dopaminergic activation, you should stay clear from the DA-agonists.
Piribedil causes the least sleepiness of the not-ergot-DA-agonists, while it comes in an XR-formulation that lasts 24 hours.
Abilify is a wildcard since it can (and most probably will) also antagonize dopamine extremely potently. It isn't extremely expensive when bought online, though. You should of course buy the generic, unless you collect brand name pill boxes or something.
I don't think AZILECT is very interesting. In doses of 10mg or less, the amphetamine metabolites of selegiline are probably barely noticeable. Azilect is way too expensive, too. Dave Pearce has tried Azilect and found it to be inferior to selegiline.
poster:Brainbeard
thread:909139
URL: http://www.dr-bob.org/babble/20090721/msgs/909280.html