Posted by deprime82 on July 30, 2009, at 11:29:13
In reply to Re: any success with dopaminergic meds?, posted by Brainbeard on July 29, 2009, at 15:13:18
hey!
i too have thought of using amisulpride, but then i've read about the clinical tests that it raises prolactine at ten-fold already at doses of 50mg -> i really don't want to get female breasts etc. because of hyperprolactinamea.
piribedil sounds like an option, but i don't know if it's prescribed in europe. i just would like to have the benefits of dopaminergic stimulation, such as mood elevation, having motivation and energy, pursuit of goals, having aims in life and so on, WITHOUT ending up as a nervous wreck with signs of social phobia.
i mean this was partially the case with wellbutrin, even when i took it with lexapro.
i have read too, that especially the non-ergoline dopamine agonists like requip or mirapex tend to make people tired, sleepy and nauseous. this is also something I don't want to achieve.. but on the other hand, the ergoline-dopamine-agonists make people more active and awake but are likely to cause some kind of heart disease (valvular heart disease, i think that's the english word).
even another health risk i don't want to take a chance.in addition, most dopamine agonists (except pergolide or cabergoline) must be taken 2-3 times a day, which is too much for me. a dosage of one time a day would be ideal.
then there are of course the APs like the mentioned amisulpride and also ABILIFY. but the abilify is way too expensive, i don't think insurance will cover a med of 450 euro per month only because i want to get a little more motivated;)
an interesting option would be AZILECT, which is basically very similar to SELEGILINE - also a MAO-B-inhibitor, but without the amphetamine metabolites that SELEGILINE possesses.
i'd be curious if someone has already tried AZILECT (rasagiline), which is normally used for parkinson's and which is thought to provide a "cleaner" and smoother feeling of motivation and dopamine flow than selegiline...
dep82
poster:deprime82
thread:909139
URL: http://www.dr-bob.org/babble/20090721/msgs/909265.html