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Benzos heading towards a good place

Posted by shasling on May 6, 2009, at 5:48:00

Most wont disagree the common bensos are best for chemical depression,how the motorskills and sedation and depression seems to scare people off from using them.

Well on the pipeline as we speak is a brand new benzo med,so now it is just refercened as a number now with no actual brand name.

This benzo is unique because appearntly they are on the verge of being more precise on the benzo sitees,the goal of this med is to offer anxiety relieaf as most benzos do,however being so selective avoid comptly the sedation side effect.

I believe its this one right here but i could be wron,the one i saw was so new it did not even have a actual name for it.Heres a snip of another i found as well as the link

"" Imidazenil is an anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil and bretazenil.

Imidazenil is a GABAA partial agonist[1] with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative[2] or amnestic[3] effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold,[4] and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present.

This unusual profile of effects makes imidazenil potentially a very useful drug. In animal studies it has been shown to be an effective anxiolytic and strong anticonvulsant, yet without many of the side effects associated with other benzodiazepines; it does not produce tolerance[5] or dependence,[6] reverses the amnestic effects of conventional benzodiazepines, and does not potentiate the effects of alcohol.[7][8]

Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety,[9] a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents,[10][11] and as a novel treatment for schizophrenia

This unusual profile of effects makes imidazenil potentially a very useful drug. In animal studies it has been shown to be an effective anxiolytic and strong anticonvulsant, yet without many of the side effects associated with other benzodiazepines; it does not produce tolerance[5] or dependence,[6] reverses the amnestic effects of conventional benzodiazepines, and does not potentiate the effects of alcohol.[7][8]

Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety,[9] a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents,[10][11] and as a novel treatment for schizophrenia.[12]

Heres the link
http://en.wikipedia.org/wiki/Imidazenil


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poster:shasling thread:894445
URL: http://www.dr-bob.org/babble/20090505/msgs/894445.html