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Re: Anti-glutamatergic cocktail. » uncouth

Posted by SLS on April 28, 2009, at 22:10:36

In reply to Re: Anti-glutamatergic cocktail., posted by uncouth on April 28, 2009, at 16:04:48

> Scott why not try Riluzole again with your current combo? Seems much more reliable than Topamax which seems anti-glutamatic in only its tertiary effects.

Thanks for reminding me about riluzole. I had forgotten that it was a glutamate release inhibitor. I just figured that Lamictal was enough as far as glutamate release inhibition was concerned.

I don't understand the pharmacodynamics of Topamax as well as you do. Through what mechanisms does it act as an antiglutamatergic drug?

Thanks.


- Scott

 

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