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Anti-glutamatergic cocktail.

Posted by SLS on April 28, 2009, at 14:32:27

I am considering using a multimodal strategy to reduce glutamatergic (GLU) neurotransmission. I suspect that this will help increase limbic dopaminergic activity via disinhibition. I suffer from bipolar depression.

1. Lamictal (lamotrigine)
2. Namenda (memantine)
3. Topamax (topiramate)

Each of there drugs are known to reduce glutamate neurotransmission via different pharmacological mechanisms.

I have been taking Lamictal for quite a few years now. I recently added Namenda to my treatment regime. So far, I think it might be helping. If, however, I reach a response plateau, I will then ask my doctor to add Topamax.

Currently:

Parnate 80mg
nortriptyline 150mg
Lamictal 200mg
Abilify 20mg
memantine 20mg


- Scott

 

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poster:SLS thread:893306
URL: http://www.dr-bob.org/babble/20090426/msgs/893306.html