Posted by yxibow on April 10, 2009, at 2:07:28
In reply to Re: Zoloft YXIBOW, posted by Phillipa on April 9, 2009, at 12:19:58
> Jay if 250 maybe 300 mg is the max how did you take the high dose of luvox fast metabolizer? Phillipa
300 is only the FDA guideline -- it is up to the physician to decide an appropriate level, especially in light of someone who has had a past of significant OCD.
At the time, it was a try at reducing my dopamine levels, as SSRIs can downregulate dopamine. It worked a little bit. At the time I was hesitant about APs, eventually I took the Luvox along with Seroquel.
No, actually I didn't have any major problems, other than slight nausea between dose adjustments.
Yes, I am a fast metabolizer, for some medications.
At 450, however, while hiking or doing any major exercise I had 'electric shocks'. Returned back to around 400 I believe. But this was a different medication mix, some years ago.
Depending on genetics and other factors, people respond differently to doses of SSRIs.Some people cannot take a significant dose possibly because their liver works differently.
Those who are older or especially elderly may require a lower dose also due to however the body processes out the medication.
I'm not saying lots more is always the greatest plan -- the minimum effective dose (MED) applies to a lot of medications, especially APs.
It's a voluntary thing, a relation with a psychiatrist, its not supposed to be masochism. And I know, this could start an anti-psychiatry thread which I really am loathe to subscribe to.
My point there, is that a dose should be discussed, the benefits should outweigh the risks, and it should be raised with due caution until results are seen, which with SSRIs, for example may not be fully seen for up to 12 weeks, but some signs will be seen much earlier.
Yes, some SSRIs people will not be able to take -- when I had some serious depression I barely managed to get on a dose of Lexapro with many GI symptoms and I abandoned it. Anyhow that's a time I'd rather not vision, but this has nothing to do with this discussion.
So, basically, go with a dose that aims to calm and quell some of the OCD -- there is no miracle cure and no drug will completely stop OCD, and there are many types -- pure 'O' or repetitive thoughts are hard to manage, I know personally -- so its basically going through at least a few SSRI trials at a working dose to see what is best.
-- tidings
Jay
poster:yxibow
thread:889581
URL: http://www.dr-bob.org/babble/20090408/msgs/889763.html