Posted by Vincent_QC on February 14, 2009, at 10:33:47
In reply to Re: Not tolerating Clomipramine well, which TCA to try, posted by Incubusfan on February 13, 2009, at 15:49:20
> Hey Vincent,
>
> I've previously tried EMSAM and Parnate. EMSAM didn't really do anything, and my body can't tolerate Parnate. It causes such terrible fatigue that I'd be out of breath going up the stairs in my home; it also caused severe hypotension for me. I do believe it helped me a bit though.
>
> I'm now on 2mg of Trilafon(an anti-psychotic), and 50mg of Clomipramine a night. I managed to drag my *ss to the gym on Wednesday, as it was a normal gym day for me(I go 4 days a week typically). However, this morning I didn't have the energy to go until it was about 11am, so I decided to just take a needed day off from it.
>
> I think I need to drink Coffee in the morning to wake me up while on he Clomipramine. I'm also hoping it doesn't make me fat. I've also got body dysmorphic disorder, so I'm well aware of how I look and what I eat. We'll see if there are any metabolic changes taking place. I'm 5'11", 145lbs, and somewhat toned, somy body fat is low, but Paxil got me up to 195 back in 2002, and Zoloft up to 180 back in 2003...
>
> Let me know how you're doing, and keep me up to date.
>
> - MikeHi Mike!
Hummm ok I see...I'm only at 20mg of Clomipramine so I assume that dosage is too small to produce side-effects on me...Normally, i'm very sensible to the side-effects of all the AD's...I Will see it in 5 days...I will be at 50mg/day like you...Like Scott write often, TCA's side-effects fade away with time...The sedation and the lack of motivation and energy is normal I think, all the AD's do this, even the ones who work hard on the DA...
I also had a really bad reaction to the Parnate. I had the same physical fatigue than the one you got... One night, I was walking on the street with a friend and he was walking normally, not fast...but I was unable to follow him...I was so tired..I was feeling hurt in each muscles of my body, like I was on fire...it was really strange...and the high BP was untolerable for me, I have to get my heart check the 26th February (EGK) because of the Parnate, since I stop it, my blood pression never return to the normal level I had before the Parnate... So a good EGK will help me to see if something goes wrong with my heart...
I can't try the Emsam patch...that's weird...in the Canada, it's approved by Health canada...but the compagny who produce them don't sell them in the Canada, so the only way is to import the Emsam patch in the Canada...but it's not in the schedule F of drugs that can be imported in the Canada... So that's a no issue... My PDoc already send my folder to Health Canada to import some Marplan in the Canada, my folder will be study soon...it will cost nothing for me if it's approved...but that's a long process...so for now, I will hope the Clomipramine will work...
Did you take the 50mg in one dose or you divided it in 2 doses??? Maybe take it before bedtime will help??? It's what I do for the 20mg...one dose at bedtime...I Will do the same at 50mg...
I also take an anti-pcyshotic to help me to sleep...50mg of Seroquel...it was helping me a lot at the begining but it begin to loose the sedative effect on me...I begin to be awake at 3-4 AM...I have to try really hard to return in my bed and sleep a little bit more...I Will need to increase my dosage to 75mg I think... I don'T know if it will be dangerous to take such a high dosage of Seroquel with the Clomipramine??? Maybe Scott can answer to this???
For the coffee, I understand you...that's the only thing that help me to stay awake at daytime...I try to limit my intake of coffee to 2 big cups in the morning, to be able to stay awake until noon...I always do a nap in the afternoon...and I drink another cup at the end of the afternoon just to give me some energy to take a shower and get dress...and go out of the house...sometimes I drink 2 cups in the afternoon...Anyway, coffee for me don'T disturb my SAD or worse it...BUT coffee worse my panic disorder and my general anxiety...so in other way, it's probably not good for my SAD...but anyway, I always feel more sociable when I drink some coffee...I can interract more well with the others... I find the coffee to be more stimulating than the Ritalin at 20mg dose...that's weird...my brains are probably just a little bit too f*ck up...
For the weight gain...I think it's different for everyone... You see, in 1 1/2 years, I gain more than 20 pounds on the Prozac + Remeron... After I was switch to the Zoloft, who do nothing on me except the weight gain...so I go from 180 in october 2007 to 230 in march 2008...After the Zoloft fail, I do a very strict diet (600 calories day), with protein shake only...and a lot of vitamins...In 2 months, I return to 175 pounds...i'm 6 feet...I was looking like an anorexic guy... Ho I forget, I got a gastric by-pass to loose weight 7 years ago...soon 8 years...I go from 450 to 175 pounds in less than 9 months...I was able to stay at 175 from 2002 until October 2007...
After the summer, I was put on the Cipralex AD...with Ritalin and after with Wellbutrin...From August to November, I gain 50 pounds...i'm now again at 225 pounds...but it'S seem to stay stable for now... I also hope the TCA's will not make me ganing weight...I Can't take another 40 pounds...I think if the Clomipramine work and I can tolerate it well...I Will do another strict diet to loose some weight before the summer...I feel just so fat now...I hate that...and it'S activating my BDD disorder...
Anyway...keep me inform of your situation...I will do the same when I will jump into the 50mg dose /day...I really hope I will not have the same side-effects than yours...
Take care of you ok !!!
Bye!
Vincent ;-)
poster:Vincent_QC
thread:879244
URL: http://www.dr-bob.org/babble/20090213/msgs/880069.html