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Re: Memantine vs Amantadine (what difference?)

Posted by psychobot5000 on February 3, 2009, at 21:28:48

In reply to Re: Memantine vs Amantadine (what difference?) » psychobot5000, posted by jms600 on February 3, 2009, at 16:09:11

> I tried memantine a few years back on an unrelated drug trial. I found that not only did it have some antidepressant properties but it also made me feel much more calmer.
>
> I was also taking Prozac at the time and the two drugs together tended to make me feel a bit 'spaced out' sometimes.
>
> To be honest it's a medication that I would like to try again; however, I really don't think my p/doc would prescribe it.
>
>

Hi jms--very interesting post. I was started on memantine yesterday (sorry to hear your p/doc isn't likely to prescribe it), and have so far had much the same experience.

After two doses (10mg), memantine has elevated my mood substantially, for a few hours after each dose (I wonder whether the effect will last). But it also is making me feel 'spaced out' now that I'm partway through day two...detached would be another way to describe it--I'm guessing it's the same thing as you (jms600) describe. I'm hoping it will pass off as I become used to it. On the other hand, as a depressive, I'd certainly like the mood elevation to stay--though I doubt that's terribly likely. My mood already seems to return to baseline within eight hours or so.

Taking memantine to combat my Agomelatine-induced exacerbation of OCD symptoms. If it works for that even a moderate amount, without causing any unacceptable side-effects, I will be very pleased.

And Scott, thanks for the note on Memantine/Amantadine. I think that explains my question--much appreciated.

Psychbot


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