Posted by yxibow on December 14, 2008, at 5:49:00
In reply to Re: 'mental illness, in brain scans', posted by rjlockhart04-08 on December 13, 2008, at 15:51:51
200mg for sleep of Seroquel sounds rather high, that's a psychotropic dose, and at any rate, Seroquel, just like any other AP, should be eased into, starting at 50mg to prevent dyskinetic reactions, among other things.
A sleep dose is normally about 25-50mg.
Its half life is just 6 hours not 12, so would be fully eliminated in about a day. The evidence though is that for almost all situations it is used once daily, almost always at night, for its primary use.
I'm not sure where Compazine comes in, its a rather old conventional agent, a phenothiazine not used for AP use really but for extreme nausea as you noted, and unless there's some confusion between it and Clozapine which was the first atypical and definitely is monitored for agranulocytosis, Compazine isn't particularly noted for that.
It is noted for potentially strong EPS (believe me, the treatment was almost worse than the situation when I had a nasty flu in college, it caused the most intense akathisia that I wanted to smash through the walls, finally they gave me IV benadryl which wore off and I could barely tell the taxi driver to take me home)
Perhaps for yourself, I think other benzodiazepines can also help panic, such as Klonopin, besides Xanax -- which admittedly is much less subtle and has a faster uptake although does not last very long and as a shorter acting benzodiazepine can possibly cause habituation earlier over time.
Stimulants and benzodiazepines together sound more like fire and water -- its rather hard to break through a lot of stimulants with a benzodiazepine or vice versa to appreciate their purpose.But then again all of these may be your own personal experiences, we are all different.
-- Jay
poster:yxibow
thread:868400
URL: http://www.dr-bob.org/babble/20081214/msgs/868674.html