Posted by yxibow on December 13, 2008, at 0:53:19
In reply to 'mental illness, in brain scans', posted by rjlockhart04-08 on December 12, 2008, at 23:13:40
> Loggin in....
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> Anyways, Why are doctors so "rampant" on Seroquel? is it the drug companies that are paying them extra for a "reward" when really it's not for the patient and causes depression, and slowing of mental thinking.Hmm... I mean I think you're entitled to your view but it sounds a little bit like a conspiracy. I mean I admit that when I was first "offered" olanzapine when it came out when I was still in college I said no to it, there was no reason for it for dysthymia -- I don't know, but then this doctor was a benzophobe -- ugh, don't really want to go back to that memory.
I mean yes, sure, its not that they are paid, well, who knows, I mean there can be doctors who have taken part in graft, but I suppose some do follow using substances off label in non-evidence based psychiatry circles just when they come out, as opposed to being a little bit more cautious and wait for some results to be seen.
That being said, Seroquel is probably, not in terms of the problems (and I am unfortunately trying to fight that) of weight gain that not just it but Risperdal and others have, the safest AP around in general opinion when used in MED (minimum effective dose) as far as other serious problems for most people, EPS, etc.
I know I have had serious results from it but I am very sensitive to certain things and they're rare, I do think it is for a patient's benefit when other agents have been tried and haven't worked, for TRD augmentation, to improve their functionality and outlook on life.
That being said, all APs have the potential of blunting, which is what you are describing and actually is a benefit for cases of agitation in schizophrenic and other related conditions, I'm assuming, if you have been prescribed it before for off label reasons.
> See, i understand, today....the use of mood stablizers has increased...Lamicatal, Geodon, Abilify (both antipsychotic's also) which... really "antipsychotics" are mood darkener's in some cases, other cases...they bring relief, so you can function. Obviously because it's a degrulation of dopamine, and serotonin, that cause "awkward behavior".
Again I'd disagree about darkeners, unless the medication is not effective for you -- APs are not always the choice for everyone, if I recall I thought you responded better to stimulants? I don't remember. It all depends on the patient.
Oh I think there's more in play than just dopamine and serotonin, and "awkward behavior" is kind of pejorative if you've gotten that sort of commentary towards you. Noradrenergic is also in the mix and then the further unstudied sigmoid and kappa and other centers regulate the brain.When it's said that "substance X functions by a possible downregulation of Y, but the exact function isn't known...." in prescribing information, that really is sort of the case, in part -- we are still in the early stages of discovering things.
That's why mapping tools are useful in patient studies for researchers but may not give what a particular consumer is looking for a pleasant view necessarily and the costs are carried by them, not by government and private grants.
As for Lamictal, it is a evidence based antidepressant in its own right, although not for everyone either and must be carefully used because of its potential but rare effects.
And certainly in bipolar disorders, Depakote and Lithium have been time tested. Trileptal is probably a better agent than Tegretol, etc. I think the fact that a number of AEDs have other uses adds to the chances that patients can live more functional and productive lives, as I noted before, with TRD a problem for a smaller but definitely serious for a number of patients
> http://www.nytimes.com/2005/10/18/health/psychology/18imag.html?pagewanted=2
poster:yxibow
thread:868400
URL: http://www.dr-bob.org/babble/20081204/msgs/868418.html