Posted by Vincent_QC on November 29, 2008, at 6:28:26
In reply to Re: No more responses?, posted by Michael Bell on November 26, 2008, at 11:05:38
> Sorry, but I thought I would get more responses on this topic. Thought there were a lot more Nardil users on this board. Please, if you are a Nardil user and don't mind taking the time to reply, kindly do so.
I just ask the question this week on another thread and I recieve no answer...
I read so many bad comments about the new nardil formulation that I just begin to think about the fact that I will loose my time again.
On other hand, I think a lot of people with social phobia and anxiety tend to listen too much to their body...I don't want to generalise, but for someone who is anxious, that's normal to listen to every signs your bodies give to you...and just to know that the formulation of the Nardil change, it can make some people to have bad reactions. Maybe i'm right, maybe i'm wrong...Who know ? We even don't know if all the antidepressants drugs have more "placebo" effects than real effects...since a lot of studies was not show to the general public, and a lot of them show results of placebo vs drugs with a maximum of 10 % difference...so that's not what I call a good result...If the Cipralex show a remission of 33% for depression and a 23 % of success in the placebo group, that's mean only 10 % of people really benefit from the Cipralex improve. The same apply to all the studies...some people just look at the drugs groups and forget to also take a look at the placebo results...Anyway's, i'm out of subject now...
I know the only differences between the new Nardil and the old one seem to come from the removing of the innert ingredients, so it's why I think it's just a false impression people have, they are anxious so they have a reaction, a positive one or not... I don't know if someone understand what I mean???
I put some links on my thread about the new formulation VS the old one. I will have to see by myself if the new Nardil is effective or not. It's the best way to know it.
Nardil is not the only one drugs to be reformulated in the past year, a lot of generic drugs are like this now. Yes, some studies also point the facts that generic drugs seem to be less effective, but this is different for everyone, some people will see a difference, others not.
I also read a lot of threads about the Clonazepam intake at the same time than Nardil. Again, for someone who never take a anxiolytic drug before, it can be magic, and this relief of anxiety will certainly be fast...but it will not come from the Nardil...it's will be the Clonazepam action on the Gaba receptors.
A lot of studies also show a change in the gaba receptors of the peoples who take anxiolytics drug after a couple of months, in fact, a destruction of a these receptors... It's probably why a lot of people have to increase the dose after a little while or switch to another one more potent and addictive like Xanax...but it's a never ending circle...and the more you take of them and the more you will have some bad effects like cognitive impairements...
I do believe that if you already take an anxiolytic drug in the past, and you are new with the Nardil, you will not find the Nardil very effective just for the social phobia at first, whatever the dose you take. Since the change, in the gaba receptors, caused by the use of the anxiolytic drugs seem to be permanent, I think the Gaba effects of the Nardil will not be very perceptive and will just became evident after a lot of time.
That's my point of view and my experience also.
poster:Vincent_QC
thread:864940
URL: http://www.dr-bob.org/babble/20081123/msgs/865693.html