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Re: SSRIs, REM sleep and memory

Posted by linkadge on October 19, 2008, at 14:59:36

In reply to SSRIs, REM sleep and memory, posted by NKP on October 19, 2008, at 12:17:23

The problem is that these parameters are likely measured in depressed subjects. The drugs could have a considerably detrimental effect on memory which is only counterballanced by the memory enhancing effects of improvement in depression. This is kind of like how you actually see some studies showing ECT can improve memory. I don't think ECT itself actually improves memory directly.


Studies in mice show that SSRI's do impair the ability to learn new tasks yet have some ability to improve performance on skills that have already been learned.

I think SSRI's probably do have adverse effects on memory. Nardil is probably the strongest REM supressing AD and it is generally considered a dumb drug.


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