Posted by bleauberry on September 21, 2008, at 21:50:56
In reply to Selegine + DLPA = BIG disappointment for me, posted by Amigan on September 20, 2008, at 17:41:10
I thought the liquid deprenyl was a lot more reliable than the pills. My experience anyway.
DLPA can have immediate effects, but sometimes not. In old clinical studies it was dosed for up to a month before improvements were noted. In those studies only 150mg were used. On the internet some places claim up to 3000mg per day. So ya know, who knows. It is hit and miss self experimentation. But then, all of psychiatry is like that, so nothing new there.
Anyway, the first week improvement was probably feeling the extra NA and DA. The fact that it faded away doesn't mean it won't work. You perhaps felt something that was not the true therapuetic effect, which takes weeks or a couple months to happen. You felt a sudden rush of norepinephrine and dopamine. Now you are accustomed to it, and the rush is gone. But that rush was not the therapeutic effect. Brain adaptations have to take place, and that takes time. You might want to stick it out longer. 10mg by the way is not an adequate dose according to studies. You may need to get to 20mg to 30mg. Lay off the DLPA if you do that.
There are built-in governors by our genes that control how much tyrosine and/or phenylalanine get converted to norepinephrine/dopamine. Yours might be set in such a way as to not produce much, no matter how much of the raw ingredient you supply. Just a possibility. If that were true, then a higher dose of deprenyl would make sense.
Don't know. Just sharing some random thoughts on the subject for you to ponder.
poster:bleauberry
thread:853148
URL: http://www.dr-bob.org/babble/20080915/msgs/853336.html