Posted by Amigan on September 20, 2008, at 17:41:10
I've been taking Selegiline for some time and it has basically pooped out. It was great at the first week but later, its effect started to slowly decline. I think it's because full MAO-B inhibition has been achieved and therefore there is not much point in taking more Selegiline until the body produces a certain amount of MAO-B again. What do you think?
Anyway, back on the subject:
I read nothing but good-to-excellent reports about the Selegiline + DLPA combination and so, i finally got some DLPA capsules to try it myself.
It was a big disappointment for me when i tried it and didn't feel anything at all. It was like i took placebo pills...
Why most people report feelings of "marked anxiety and insomnia", "great improvement in mood", etc and i have nothing to report. What did i do wrong or what is wrong with my neurochemistry?
Let's see:..
- I took 10mg of oral Selegiline after breakfast, as i'm supposed to.
- I waited for many hours without eating anything (as DLPA gets absorbed well only in an empty stomach) and took 1 capsule (500mg) of DLPA.
- After almost 1 hour, i took another capsule and this time, i combined it with a B-complex pill which contains 200mg of B6 (Pyridoxine) to help the absorption of DLPA.So, why did it failed to give any results? Possible causes that i can think of:
- At first, i thought that the DLPA has expired because the bottle says that it expires at "1010" and i didn't know what this suppose to mean, but the pharmacist told me that it means the 10th month of 2010.
- I have never used a REAL stimulant. Thus, tolerance to stimulants should be excluded, imho.
- I drink a lot of coffee, though! Does caffeine produce cross-tolerance with other stimulants?? Does it "get in the way" to this combo? I would rather think that it should act synergically, but i'm not sure...
- Could the Prozac i took about 4 days ago interfered somehow? Personally, i doubt it as it works on Serotonin, while Selegiline/DLPA works on DA/NE, unless it has something to do with liver enzymes induction...Your thoughts?
poster:Amigan
thread:853148
URL: http://www.dr-bob.org/babble/20080915/msgs/853148.html