Posted by Marty on July 24, 2008, at 10:29:33
In reply to Re: Agomelatine- Anyone tried it? Share your Info pls!, posted by Negcreep on July 24, 2008, at 3:44:55
> Hi Marty thanks for the list, yeah I often check that website thanks. I'm interested in Agomelatine for a couple of reasons. Firstly it is allegedly as effective as current first line treatment (SSRIs) but has a much much better tolerability profile.
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This is also why I'm interested into it. I can't stand the side effects comming from typical serotonergic antidepressant. They only thing that makes be ambivalent toward Agomelatine is that Melatonin makes me depressed in a couple days and I wonder if it is significant or not. I'm not sure it is and to bring a comparison that sum up my logic: Tryptophan(5-HT precusor) makes me anxious but SSRI is anxiolytic to me. Stimulating a receptor by ingesting his precursor (ie Tryptophan) or his own endogenous neurotransmitter (Melatonin pass the BBB, Serotonin does very poorly) does induce the same effects as inhibiting his reuptake .. and so I may as well forget my reaction with Melatonin and stay positive toward Agomelatine.... IF you have some thoughts about it plz share.Btw, if I ever make some "Side Effects Suck!" T-Shirts.... want one ? ;)
/\/\arty
poster:Marty
thread:841653
URL: http://www.dr-bob.org/babble/20080718/msgs/841761.html