Posted by Amigan on June 6, 2008, at 13:28:01
In reply to Re: Nitrous Oxide, posted by undopaminergic on June 5, 2008, at 14:22:04
> >
> > I also read somewhere that high amounts of N2O causes brain damage.
> >
>
> The so-called Olney's lesions? It seems that all substances with considerable potency as NMDA-antagonists are capable of causing this pattern of damage, at least in some species. As far as I know, Olney's lesions have still not been observed in monkeys or primates, and in this case, there is a considerable probability for differences between rodents and more advanced species, as in the latter, the brain structures implicated in Olney's lesions are very much more advanced.No, i don't think it was about Olney's lesion. It was either about excessive nitrogen being neurotoxic or simply about hypoxia caused by erroneous N2O/O2 ratio. I can't remember.
poster:Amigan
thread:832870
URL: http://www.dr-bob.org/babble/20080606/msgs/833311.html