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Re: This CAN NOT be possible!

Posted by undopaminergic on May 26, 2008, at 10:48:18

In reply to Re: This CAN NOT be possible!, posted by mari stella on May 25, 2008, at 19:29:16

>
> Possibly, the use of this type of stimulant in combination with low doses of sulpiride or amisulpride might be a solution.
> *********Is this something a Dr would be OK with?
>

I don't think it's a controversial combination in any way, but unfortunately, neither sulpiride nor amisulpride are FDA-approved, so you would probably have to import them.

> > Quite so, but there have been a few reports from people having tolerance problems with amphetamines suggesting that it does work.
> *********Can you show me where? I am desprate for HOPE right now.
>

See the "Neurotransmitters" board on this site, or search the web for suitable keywords (memantine, amphetamine, tolerance, etc.).

> > Personally, I've found that memantine has some stimulant-like effects of its own, and therefore it's somewhat difficult to say how much of its effects are a result of its reduction of tolerance to stimulants, as opposed to stimulant effects of its own.
> *********WHAT??? Are you saying you dont know if it is working as a tolerance reducer or their just enhancing each other?
>

Approximately. It's also difficult to rule out the possibility of more complex interactions between the drugs - for example, they may potentiate each other in some ways, and antagonise each other in other ways.

> I AM going to try this and if the mementine helps me get more than 3 days out of adderall then I guess it works. For what I need anyway.
>

I wish you good luck.

>
> Therefore, the use of kappa-opioid antagonists like buprenorphine in combination with stimulants is a promising approach to solving the problem of tolerance.
> **********Im on both...obviously no help to me...(whaaaaaa!!!!)
>

That's quite a coincidence! How often to you take buprenorphine, and at what dose? Do you find tolerance to be a problem with this drug too?


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poster:undopaminergic thread:829948
URL: http://www.dr-bob.org/babble/20080519/msgs/831201.html