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Re: Pergolide for Bipolar. @ SLS, your comments pl

Posted by undopaminergic on May 21, 2008, at 7:11:06

In reply to Re: Pergolide for Bipolar. @ SLS, your comments pl, posted by SLS on May 17, 2008, at 9:21:09

I recommend against the ergoline-based dopamine agonists. There's a serious chance that they will mess up your cardiac valves if used in the long term, and another risk is fibrosis.

MAOIs, stimulants, memantine, amisuplpride/sulpiride, or a combination of them is preferable.

> Hi Gary.
>
> You could try Dostinex (cabergoline) or Trivestal (piribedil) as DA agonists.
>
> How did Wellbutrin treat you? What about Emsam?
>
> I am dubious that DA agonists will work for severe depression. My impression is that they don't work for very long before you get diminishing returns. I have seen this with pergolide. You could try Abilify in combination with Wellbutrin and Lamictal. It is a partial DA agonist. You might want to consider going with Nardil or Parnate. These MAOIs do a better job overall than Emsam.
>
>
> - Scott
>
>
> ****************************************************
>
>
>
>
>
> > Hi to whoever's reading this post.
> >
> > I have always responded well to Dopaminergics. Pramipexole 'almost' gave me full remission, or very, very close anyway. I tried Piribedil and Ropinerole with less effect than Pramipxole, so went back to Pramipexole. Unfortunatley it didn't work half as good at the first time, very saddening indeed...
> >
> > I have since been looking for more Dopaminergics to try, especially one's that antagonise the D1 receptor. At present the only one on the market that even goes close to D1 is Pergolide. I was wondering if anyone had had any experience on this med? Bipolar's (type II/NOS) reply preferably but all comments welcome! :O)
> >
> > Thanks
> >
> > Gary
>
>


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