Posted by Racer on May 17, 2008, at 10:15:11
In reply to Pergolide for Bipolar. @ SLS, your comments pls?, posted by garylee on May 17, 2008, at 8:36:15
Pergolide is used to treat Cushing's in horses, and one symptom it seems to improve is depression. Of course, we don't know their subjective experience, but the pergolide does help them...
It's an interesting question. How would you rate your depression? Do you suffer severe, moderate, mild, variable depression? That might also make a difference.
Also, I don't tend to find it all that helpful to say, "oh, I need to boost this neurotransmitter or that." I find it a lot more helpful to say, "The medications which have helped me most have shared these characteristics as far as mechanism goes..." The neurochemistry of our brains is far more complex than anyone yet understands. I have no doubts that the ratios are more important than actual amounts of the three catecholamines we discuss most here.
It's worth considering those unexpected choices -- such as pergolide. I think, though, that it might be more helpful to consider them due to their effects in the body and even their side effects -- rather than concentrating on mechanism of action to any great degree.
Good luck.
poster:Racer
thread:829642
URL: http://www.dr-bob.org/babble/20080510/msgs/829656.html