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Re: SAMe Combined with Antidepressants.

Posted by tarheelex on May 14, 2008, at 15:57:13

In reply to Re: SAMe Combined with Antidepressants., posted by undopaminergic on May 11, 2008, at 18:01:22

I have found Sam-e to work moderately well at smaller doses. 400 mgs seems to be ok although there is some mild anxiety and gastro side effects. It seems to be hitting NE receptors more significantly than serotonin. Currently augmenting with trazodone for the anxiety and some insomnia. 5 days into this augmentation trial. Sam-e builds up in your system over time and the hope is that I can eventually go down to 200 mgs although I am typically a decent responder at low doses.


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