Posted by ace on May 11, 2008, at 23:19:05
In reply to Re: Nardil- The best AD ever......., posted by simon79 on May 10, 2008, at 20:54:42
> Hi Ace,
> scoobydoo_126@hotmail.com
> Thanks a bunchCheers mate....I have dug them out! These files date back 7 years. At this stage I was printing out EVERY possible post/trial on Nardil, on any site, I could find (Heaven forbid, I might be just a tad obsessive!!!)
Reading through them again just verified what I have stated for the past years in regards to Nardil.....Out of all the anectodes, and it would take me a week to count them all!) I remember encountering 1-3 in which a person did not respond to Nardil- and even in these cases, I can see reasons why they would not have responded. I might sound very bias....but all this is on paper, in clinical trials, etc etc. It still amazes me.
Here we go..... In addition to these I have PDF's with no URL, which I will have to locate manually, as such....
I have many many more than I will show here, so please ask if you would like more....
1. ""MAO inhibitors:
An option worth trying in treatment-resistant cases """
Jonathan O. Cole, MD
Senior consultant in psychopharmacology
McLean Hospital, Belmont, MA
Professor of psychiatry, Harvard Medical School
J. Alexander Bodkin, MD
Chief, Clinical Psychopharmacology Research Program
McLean Hospital, Belmont, MA
Assistant professor of psychiatry, Harvard Medical School
This is an extremely good article....With regards to dose, HT crises and many other things.
"Phenelzine has the advantage that the effective dosage for depression is probably now knownmore than 1 mg/kg body weightalthough in three earlier large negative controlled studies, the effective dosage was not known and too little was given for too short a period. Weight gain and hypotension may be more common with this drug than with other MAOIs"
This statement is particulary significant.
Please locate the article here, and show your psychiatrist.....
http://www.drtonyromack.com/MAOIs.htm
2. Phenelzine 60 mg Effective: 30 mg little benefit. but 60mg helps 70% depressed. If no response in 6 weeks, increased to 75-90mg/d for fast acetylators.Lewis Ravaris, U Vermont.
(Much more great info in this)
3. b) Efficacy. MAOIs have been studied in patients with borderline personality disorder in three placebo-controlled acute treatment trials (5557).
...
Cowdry and Gardner (55) noted that, "the MAOI proved to be the most effective psychopharmacological agent overall, with clear effects on mood and less prominent effects on behavioral control."http://www.aapel.org/bdp/BLpharmacotherapyUS.html#maoi
(I do NOT agree with certain things stated here)
I have got many more here right next to me...I just got to run...let me know how you go with these!A final word from a fellow psychobabbler!....
"I will never forget what one of the Godfathers of nardil told me, Dr. Fredick Quitken .... "Nardil works for 90% of patients, but only 25% of patients can stay on it and tolerate the side effects. "
Smith
NB- I actually think the s/effects can be managed! They can be a nuiscance at times though...
Ace:)
poster:ace
thread:827439
URL: http://www.dr-bob.org/babble/20080510/msgs/828612.html