Posted by SLS on January 14, 2008, at 9:35:44
In reply to CNS research Deplin Link » SLS, posted by star008 on January 14, 2008, at 8:01:22
> http://www.cnsspectrums.com/aspx/articledetail.aspx?articleid=1267
>
> check out this article.. the fda classifies dephlin as neither a drug or a supplement.. so according to them we are both wrong
My motivation for starting this thread was to diffuse the notion that Deplin is nothing more than an expensive folic acid. My calling it a drug would hopefully change people's perspectives regarding the physiological and clinical advantages of Deplin when compared to folic acid supplements. To the best of my knowledge, L-methylfolate is not found in human foodstuffs. I imagine there are good reasons for the FDA to establish the category of "medical food" such that a prescription is required for its dispensation. If someone takes a dozen 7.5mg pills, are there any untoward effects? One 7.5mg pill of Deplin produces many times the biological availability in the brain as folic acid such that one would need to ingest a hundreds of folic acid to equal 1 pill of Deplin. Besides being the biologically active metabolite of folic acid, it readily crosses the blood-brain barrier.Regardless of the semantics, Deplin has pharmacological actions to induce the rate of synthesis of the monoamine neurotransmitters. Folic acid does not do that.
How much different is the relationship between folic acid and Deplin versus primidone and phenobarbital? Both are metabolized by the body before becoming biologically active.
- Scott
poster:SLS
thread:806127
URL: http://www.dr-bob.org/babble/20080114/msgs/806372.html