Posted by Phoenix1 on January 11, 2008, at 8:51:47
In reply to My guide.on treatment resistant depression!, posted by FrequentFryer on January 10, 2008, at 23:13:26
> Got allot out of this forum so I thought I would give something back.
>
> I have taken almost all the Anti-D's / Cocktails and there is only 1 drug that helps me through the bad times. Sure go ahead and try Effexor if it works for you good, stick with it, if it turns you into a zombie or poops out (more then likley) give Nardil a try.
>
> If your reading this you probably want to get anti-depressed ASAP, so. Get some Nardil and try to get up to the best dosage ASAP (best dosage = 1mg Phenelzine per 1 kg of bodyweight). I managed to get off Zoloft cold turkey and onto 90mg of Nardil in 8 days and experienced relief after 2 weeks. (turned from a depressed zombie to above average happy person).
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> I wasn't expecting any relief for atleast 3 weeks at optimal dose, but for some reason I am getting relief after 1 week. I think its because I have been taking heaps of fish oil and getting a good night sleep via a small dose of Seroquel (25 - 100 mg), so I would recomend those to ya, especially the Seroquel because it antagonise's 5ht2 and if it dosn't put you to sleep almost nothing will. (The MAOI's usually give ya a bit of insomnia at first).
>
> Heaps of people / doctors don't recommend Maoi's because of all the contradictions but personally I have never found it a problem.
> (Disclaimer): EVERY ONE'S DIFFERENT THOUGH!
> So at first avoid Tyramine, then when the Nardil is at a steady plasma level you can try eating a bit of cheese, then try and get your blood preasure checked 40 minutes later. (Tyramine and Tryptophan is pretty safe with Nardil I find).
> Back in the day Pdoc's used to try and treat people with MAOI's and Amphetamines. THIS I DON'T RECOMMEND! Probably the worst contradiction of any drug combination, also definatly stay away from MDMx.
> Other MAOI's when taken with Nardil is probably your biggest worry. (ie chocolate, veggie might etc), but I wouldn't worry about them to much, they don't bother me any but again everyone is different so take the same precaution as with the Tyramine.
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> Now I would say taking 1mg of Nardil per 1kg of bodyweight with the right diet & sleep etc is 90% likely to Antidepress the worst of case's (well its your best chance anyway). That being said I won't be surprised if the antidepressant effects start to diminish over time. Then you will need to add other things.. But that is a whole nother chapter.
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> Best of luck.
> FreqWow, thanks, I agree the MAOI's are vastly underused, and unjustly feared. Now, I need Chapter 2. Already worried about what will happen when Nardil poops out. It's such a life-changing drug, that I can't imagine what would/will happen if/when it poops out. Already aiming for a high dose of 90mg (1mg/kg, so increasing dose won't be much of an option.
Phoenix1
poster:Phoenix1
thread:805647
URL: http://www.dr-bob.org/babble/20080105/msgs/805691.html