Posted by bleauberry on January 3, 2008, at 19:09:59
In reply to Provigil -good for 4-5 days then make things worse, posted by 4WD on January 2, 2008, at 20:49:40
This complaint comes up a lot with provigil. Not all the time, but frequently. Not sure what's up with it. Maybe a plateau is reached with the dose and it's now time for a higher one? Maybe the drug has built up over time and is now too much? Maybe brain changes are ocurring that need time to stabilize? Don't know.
I've never done well with provigil. But I did real well with its parent adrafinil. Even with it though, the first couple weeks were strange. Felt good some days, bad some days, good some hours, bad a few hours later, high energy one minute, total fatigue the next. Adrafinil calls for doses of 600mg to 900mg a day (2 or 3 300mg tabs). I found that the 600mg dose built up over a few days to where it was just too much. I ended up staying with 300mg, gave it about 2 weeks and things were smoothing out, then at about a month I just felt better all around and couldn't even tell I was taking anything. No side effects at all. Just felt better. It was in combo with prozac. It did a good job of countering the emotional numbness of ssris.
Wish I had some good suggestions for you. Provigil is a tricky one to figure out. It might be just a simple matter of being ready for a higher dose. It might be a situation of needing another drug to balance it out, such as an ssri. I've tried adrafinil with prozac, zoloft, and lexapro, and by itself. All were lousy except with prozac where it was real good. Some good synergy with prozac. Don't know why.
poster:bleauberry
thread:803885
URL: http://www.dr-bob.org/babble/20071225/msgs/804066.html