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Effexor and Lexapro should not be taken together » nihocl

Posted by Racer on December 3, 2007, at 23:24:06

In reply to Lexapro and Effexor, posted by nihocl on December 3, 2007, at 15:08:31

In general, taking two SRIs together risks serotonin syndrome -- a potentially fatal drug reaction caused by overstimulation of certain serotonin receptors. It's not something to play around with, and I'm a bit surprised that your doctor is suggesting it.

That said, sometimes low doses of two serotinergic drugs can safely be taken -- it's just not something to try lightly. Especially since you don't remember benefiting from Effexor in the past, I'd be thinking in terms of other options.

Did your doctor discuss with you why he wanted to try this combination? What his goals were? Also, are you getting any benefit from Lexapro? Maybe switching to another drug entirely makes more sense?

Good luck.


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