Posted by anonymoose on December 1, 2007, at 12:16:34
In reply to Re: dopamine agonists??, posted by banga on December 1, 2007, at 5:47:41
My $.02 regarding dopamine agonists and MAO-B inhibitors. Dopamine agonists would be preferable for those who have low levels of dopamine synthesis, whereas MAO-B inhibition would be preferable for those with normal synthesis but overactive MAO-B activity. Is this correct?
Both can be quite effective in increasing dopaminergic function, but all other things being equal, a dopamine agonist might be better to try first, because it doesn't require normal dopamine production to work.
If a person has low dopamine function due to inadequate dopamine synthesis and not overactive MAO-B activity, an MAO-B inhibitor may not seem to help as much because it doesn't actually help increase dopamine synthesis. It just prevents MAO-B from metabolizing whatever dopamine the body already produces. It doesn't actually directly improve the problem of low production.
Comments or corrections?
poster:anonymoose
thread:797625
URL: http://www.dr-bob.org/babble/20071125/msgs/798088.html