Posted by linkadge on November 17, 2007, at 20:00:44
In reply to Re: SSRI Apathy- This is the *True* SSRI response!, posted by 49er on November 17, 2007, at 18:17:17
I think the SSRI induced apathy is multifacited. First the SSRI's usually mess with your hormones. Ie decreasing testosterone etc. They can also mess with your blood suguar.
Another issue is the possibility that prolonged REM supression actually produces the apathy. REM sleep may be depressogenic, but it is also when growth hormone release occurs. Supressing REM sleep with SSRI's could adversly affect motivation this way.
To reduce apathy, I would use the lowest possible dose. Try dosing in a way that is least disruptive to sleep. Exercise, and perhaps try some form of dopaminergic augmentation.
A low dose citalopram/burpopion combination might work.
Linkadge
poster:linkadge
thread:793535
URL: http://www.dr-bob.org/babble/20071115/msgs/795635.html