Posted by Astounder on November 15, 2007, at 22:53:13
In reply to Re: Tolerance to Provigil is probably only hepatic., posted by Fivefires on November 15, 2007, at 21:35:35
Since it's metabolized hepatically, any way that ignores the portal vein system should work; honestly, though I haven't done so, you could try insufflating it--right to the brain. If I remember the pills, they too large to do sublingual.
They felt really different for me. Adderall made me feel great, that I could do anything, let's clean my room, let's clean the bathroom. Teeth clenching--no need for food. I began a lot of projects at once that I would forget about and start another. I was very talkative and social. 12 hours later I was in the depths of an extremely hostile, irritated depression, intolerable of frustration, left crying and ashamed. I became very sad and disappointed when I went off of it. Very similar to the way I felt when I went off EmSam.
Provigil made me much more reactive than proactive. A phone rang? I picked it up. Mess on the counter? I cleaned it up. Clothes are dirty? Put em in the wash. Need something from the store? I'll go out and get it. No euphoria, no anxiolysis, no psychomotor activation, just not avoidant. This was an amazing change for someone as avoidant as I am. When the drug wore off 12 hours later I became depressed again, but in a more cataleptic, apathetic way, the way I was before I started taking it.
I didn't become behaviorally sensitized to Provigil, meaning I didn't feel any compulsion to take it for the sake of taking it like Adderall. But after a few weeks, it pooped out and I was never again able to catch that spark--taking it at any dose merely made me awake & alert.
poster:Astounder
thread:793616
URL: http://www.dr-bob.org/babble/20071115/msgs/795389.html