Posted by amigan on October 16, 2007, at 18:25:58
In reply to Re: Why l-dopa doesn't cause..., posted by amigan on October 13, 2007, at 21:47:13
> > That's interesting that you didn't feel 200mg L-dopa with whatever that other thing in there is.
> > Sometimes, hardly ever, I take mucana, and one cap of that contains 130mg L-dopa and none of the other stuff that should make it happen in your brain rather than your body, and I notice that (classic dopamine feel from it, sex, a cool pool on a hot day, lying in the sun, that sort of thing).
> >
> > Interesting.
>
> I don't know... 130mg are enough to produce a psychoactive effect for you, while i didn't feel anything at 300mg except of nausea and vomiting. I can only assume that:
>
> 1. This mucana extract has either other psychoactive substances or substances that potentiate l-dopa greatly.
>
> 2. I drink fairly large amount of coffee and i read that caffeine promotes the release of dopamine.
> Could this masks the effects of l-dopa, assuming that the level of dopamine inside the brain was already high due to the action of caffeine?
>
> 3. I have some kind of "CNS dopamine insensitivity" if such thing exists.. and thus, i only manifest peripheral symptoms like vomiting (although nausea is not peripheral, if i'm not mistaken)
> Does anyone know if there is such case??
> Perhaps i should try to take a dopamine agonist like bromocriptine and see if this is the case.Ok. I got 5mg of bromocriptine today. It's the first time that i'm trying a dopamine agonist. The only thing i perceived was a mild sensation of fatigue which is included on the adverse effects list.
No libido or mood enhancement were observed, (In fact, it makes me feel rather dysthymic!) no augmentation of caffeine like this link suggest:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10996051&dopt=Abstract
no nothing.
poster:amigan
thread:788688
URL: http://www.dr-bob.org/babble/20071009/msgs/789628.html