Posted by amigan on October 13, 2007, at 21:47:13
In reply to Re: Why l-dopa doesn't cause... » amigan, posted by Sigismund on October 12, 2007, at 14:55:24
> That's interesting that you didn't feel 200mg L-dopa with whatever that other thing in there is.
> Sometimes, hardly ever, I take mucana, and one cap of that contains 130mg L-dopa and none of the other stuff that should make it happen in your brain rather than your body, and I notice that (classic dopamine feel from it, sex, a cool pool on a hot day, lying in the sun, that sort of thing).
>
> Interesting.I don't know... 130mg are enough to produce a psychoactive effect for you, while i didn't feel anything at 300mg except of nausea and vomiting. I can only assume that:
1. This mucana extract has either other psychoactive substances or substances that potentiate l-dopa greatly.
2. I drink fairly large amount of coffee and i read that caffeine promotes the release of dopamine.
Could this masks the effects of l-dopa, assuming that the level of dopamine inside the brain was already high due to the action of caffeine?3. I have some kind of "CNS dopamine insensitivity" if such thing exists.. and thus, i only manifest peripheral symptoms like vomiting (although nausea is not peripheral, if i'm not mistaken)
Does anyone know if there is such case??
Perhaps i should try to take a dopamine agonist like bromocriptine and see if this is the case.
poster:amigan
thread:788688
URL: http://www.dr-bob.org/babble/20071009/msgs/789081.html