Posted by linkadge on September 21, 2007, at 14:54:13
In reply to Re: Treatment Resistant Thoughts, posted by back4abit on September 21, 2007, at 9:27:48
I think people become treatment resistant on account of cellular problems. Antidepressants just affect neurotransmitters. If the cellular structure is not in place, or if there is atrophy/dammage, then the cell is not going to function properly regarless of how much neurotransmitter is available. The neurotransmitter is just a messenger.
Treatment resistance is probably much like diseases like parkinsons, M.S., Huntingtons, Alzheimers, etc where there is extensive cellular dammage.
The monoamine hypothsis is a product of the fact that we can alter monoamines. We can't do much for loss of cellular integrity.
Linkadge
poster:linkadge
thread:783554
URL: http://www.dr-bob.org/babble/20070919/msgs/784336.html