Posted by James R on August 30, 2007, at 15:21:38
In reply to Re: Novel cure for mental illness,, posted by linkadge on August 30, 2007, at 13:27:38
> Hmm, sounds kind of theoretical to me.
>Thanks for expressing interest in this strategy.
The treatment worked for me. Alas there is 1
data point indicating success.
I was schizoaffective with bipolar mood swings.
Also, I had a tardive dyskenia that caused horrible tension headaches and lock-jaw. The treatment cured the TD and my mood swings.
>
> >1) Start taking a medication that raises choline >levels. Norepinephrine reuptake inhibitors will >work
> >(Wellbutrin or Effexor). Also an ACE inhibitor >will do to.
>
> How to NRI's increase choline levels?
>
>I'll get back to you on this.
>
> >2) Take a PKC inhibitor with an anticholenergic >medication. The bioflavonoid Quercetin is a PKC
> >inhibitor and benadryl can be used for its >anticholenergic attribute. Step 2 will "reset" >your liver to
> >a healthy state for the mental illness battle.
>
>
> How do anticholinergics reset the liver?
> How do PKC inhibitors reset the liver?
>The anticholergic + PKC combo do the "liver reset".
I can come up with a formal proof of how liver
enzyme are rearranged with anticholergic med + PKC inhibitor. I need a a little time. Again,
I got this strategy from an aquantice.
> >Also, the PKC inhibitor + anticholenergic med >combo will do a clean sweep of dopamine receptor >upregulation (it can cure tardive >dystonia/dyskenesia and other issues related to >dopamine receptor supersensitivity).
>
> TD is not necessarily caused by dopamine receptor upregulation. There is some evidence of actual neurotoxicity, hence the preventitive use of antioxidants. Why are we assuming that dopamine receptors are upregulated?
>
>
>
> >3) After finishing 2, get off all meds (the pkc >inhibitor and benadryl and NRI/Ace inhibitor).
> >Start taking large doses of phosphatadyl choline >and inositol.
>
> >The chronic administration of
> >the 2 will ultimately *lower* the basal levels >of choline and inositol in the body.
>
> Says who?
>Supplements 101. You liver tries to maintain N units of a chemical. Next we injest a substantial
more of the chemical and we have N+M. The liver
will downregulate the natural internal production of the chemical because it wants N units.
> >This is good as choline and inositol are TMG >synthesis inhibitors. Also high choline levels >can be associated with addiction, bipolar mania >and more.
>
> Says who? Somtimes choline is effective for rapid cycling in bipolar. Sometimes bipolar mania responds to cholinergic supplements. The antimanic drugs lithium and valproate work, in part by increasing cholinergic sensitivity.
>
> Also, what disorder are we talking about here, unipolar or bipolar? For bipolar, increasing SAMe synthesis can be a very bad thing.
>I postulate that increasing SAM-E is safe with lower basal choline levels.
> Some studies have found low inositol levels in the CSF of depressed suicides.
>
> Linkadge
>
>
>Thanks for giving your time and thoughts.
Regards,
James R
poster:James R
thread:779760
URL: http://www.dr-bob.org/babble/20070824/msgs/779780.html