Posted by linkadge on August 30, 2007, at 13:27:38
In reply to Novel cure for mental illness,, posted by James R on August 30, 2007, at 12:47:45
Hmm, sounds kind of theoretical to me.
>1) Start taking a medication that raises choline >levels. Norepinephrine reuptake inhibitors will >work
>(Wellbutrin or Effexor). Also an ACE inhibitor >will do to.How to NRI's increase choline levels?
>2) Take a PKC inhibitor with an anticholenergic >medication. The bioflavonoid Quercetin is a PKC
>inhibitor and benadryl can be used for its >anticholenergic attribute. Step 2 will "reset" >your liver to
>a healthy state for the mental illness battle.
How do anticholinergics reset the liver?
How do PKC inhibitors reset the liver?>Also, the PKC inhibitor + anticholenergic med >combo will do a clean sweep of dopamine receptor >upregulation (it can cure tardive >dystonia/dyskenesia and other issues related to >dopamine receptor supersensitivity).
TD is not necessarily caused by dopamine receptor upregulation. There is some evidence of actual neurotoxicity, hence the preventitive use of antioxidants. Why are we assuming that dopamine receptors are upregulated?
>3) After finishing 2, get off all meds (the pkc >inhibitor and benadryl and NRI/Ace inhibitor).
>Start taking large doses of phosphatadyl choline >and inositol.>The chronic administration of
>the 2 will ultimately *lower* the basal levels >of choline and inositol in the body.Says who?
>This is good as choline and inositol are TMG >synthesis inhibitors. Also high choline levels >can be associated with addiction, bipolar mania >and more.
Says who? Somtimes choline is effective for rapid cycling in bipolar. Sometimes bipolar mania responds to cholinergic supplements. The antimanic drugs lithium and valproate work, in part by increasing cholinergic sensitivity.
Also, what disorder are we talking about here, unipolar or bipolar? For bipolar, increasing SAMe synthesis can be a very bad thing.
Some studies have found low inositol levels in the CSF of depressed suicides.
Linkadge
poster:linkadge
thread:779760
URL: http://www.dr-bob.org/babble/20070824/msgs/779764.html