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Re: Mirapex

Posted by kingcolon on August 23, 2007, at 13:49:30

In reply to Re: Mirapex » ChrisK, posted by Michael on August 20, 2007, at 11:40:14

>
> > For me Mirapex has alieviated a lot of my anhedonia/apathy. It has given me back some emotions that were long gone. I can actually feel good things again and don't have all of the emotional numbness that a lot of AD's gave me.
> >
> > I don't pretend to know why it works, just that it does for me. Also I didn't get any of the bad side effects.
>
> I know that this is an ancient thread, but thought I'd try asking a follow-up anyway... So, just wondering what dose/how much you were taking? Any other comments...? Thanks.
>
> michael

For me Mirapex has alieviated a lot of my anhedonia/apathy. It has given me back some emotions that were long gone. I can actually feel good things again and don't have all of the emotional numbness that a lot of AD's gave me.
> >
> > I don't pretend to know why it works, just that it does for me. Also I didn't get any of the bad side effects.
>
> I know that this is an ancient thread, but thought I'd try asking a follow-up anyway... So, just wondering what dose/how much you were taking? Any other comments...? Thanks.
>
> michael

I used Mirapex and also Requip recently, but had to stop because of palpitations which were not even dose related. Low doses were used in the studies on depression--not those in the range used for Parkinson's. It helped with anhedonia, but did cause some fatigue. I also use Cymbalta and Lamictal. I think any dopaminergic is good for people experiencing emotional dulling on SSRI's, and there is probably a subset of people with depression who experience marked benefit from dopaminergics. Here are two great articles on this subject; I bought them as a single article, and for those who are really interested, it's worth it. They are too long to post here.

http://jop.sagepub.com/cgi/content/abstract/21/5/461

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T26-4J2KTD4-2&_user=10&_coverDate=08%2F31%2F2006&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=069918af2b8388c66ed1df5b4773f8a5



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