Posted by Crazy Horse on March 28, 2007, at 13:52:09
In reply to Re: Is Lyrica hard on the Liver? » Crazy Horse, posted by Larry Hoover on March 28, 2007, at 8:02:18
> > I was taking Lyrica 300 mgs. bid, my GP told me we have to reduce it to 300mgs. a day, he said at 600 a day it may cause liver Damage. Is this true? What sucks is that Lyrica at 300 bid works beautifully for anxiety. At 300 a day i feel no help from the drug.
> >
> > -Monte
>
> I can't explain your doctor's concerns. Lyrica is almost completely devoid of liver interaction, with the major liver metabolite constituting less than 1% of the total drug excreted. Total liver interaction is thought to be less than 2%. There is no FDA warning. There isn't even a restriction or contraindication noted for those with known liver disease. Nothing in the monograph, except a notation in the uncommon side effects list of increased liver enzymes. Nothing in Pubmed. I think he may have made a mistake. Absent demonstrated increases in liver enzymes in your body....or did you have those?
>
> Lar
>No, i have not had an increase in liver enzymes in my body. I think you're right, he made a mistake. Thanks Lar.
-Monte
poster:Crazy Horse
thread:744779
URL: http://www.dr-bob.org/babble/20070327/msgs/744986.html